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Test Code CIFS Cutaneous Immunofluorescence Antibodies, IgG, Serum

Reporting Name

Cutaneous Immfluor. Ab, S (IgG)

Useful For

Confirming the presence of IgG antibodies to diagnose of pemphigoid, pemphigus, epidermolysis bullosa acquisita, or bullous lupus erythematosus

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  14 days

Reference Values

Report includes presence and titer of circulating antibodies. If serum contains basement membrane zone antibodies on split-skin substrate, patterns will be reported as:

1) Epidermal pattern, consistent with pemphigoid

2) Dermal pattern, consistent with epidermolysis bullosa acquisita

 

Negative in normal individuals

Day(s) Performed

Monday through Friday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

88346

88350

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CIFS Cutaneous Immfluor. Ab, S (IgG) 104835-4

 

Result ID Test Result Name Result LOINC Value
21539 Cell Surface Ab IgG 104831-3
21540 Basement Membrane IgG 104836-2
21541 Primate Esophagus IgG 66881-4
21542 Primate Split Skin IgG 104832-1
21638 Other 48767-8

Report Available

2 to 7 days

Reject Due To

Gross hemolysis OK
Gross lipemia Reject
Gross icterus OK

NY State Approved

Yes

Method Name

Indirect Immunofluorescence

Secondary ID

8052