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Test Code FKMS Ketamine and Metabolite Screen, Serum/Plasma

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
FKMSC Ketamine and Metabolite Confirm No No

Testing Algorithm

If Ketamine and Metabolite Screen is positive, then Ketamine and Metabolite Confirm (FKMSC) will be performed at an additional charge.

Reporting Name

Ketamine and Metabolite Screen

Specimen Type


Specimen Required

Submit only 1 of the following specimens:



Draw blood in a plain red-top tube(s), (Serum gel tube is not acceptable.) Spin down and send 5 mL serum refrigerated in a plastic preservative-free vial.



Draw blood in a lavender-top (EDTA) tube(s) or green-top (heparin) tube(s), (Plasma gel tube is not acceptable.) Spin down and send 5 mL EDTA or heparinized plasma refrigerated in a plastic preservative-free vial.

Specimen Minimum Volume

2.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Refrigerated (preferred) 14 days
  Frozen  270 days
  Ambient  14 days

Reject Due To

Hemolysis NA
Lipemia NA
Icterus NA
Other Polymer gel separation tube (SST or PST)

Reference Values

Reporting limit determined each analysis

Units: ng/mL



     Synonyms:       Ketalar


Reported levels during anesthesia: 500-6,500 ng/mL



     Synonyms:       Ketamine Metabolite


The intravenous administration of 2 mg/kg of Ketamine followed by continuous infusion of 41 mcg/kg/minute produced an average steady-state plasma concentration of 2,200 ng Ketamine/mL and an average peak Norketamine level of 1,050 ng/mL which occurred near the end of the 3 hour infusion.

Day(s) and Time(s) Performed

Tuesday, Thursday

Performing Laboratory

NMS Labs

CPT Code Information

80307 – Screen

80357 – Confirmation, if appropriate

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FKMS Ketamine and Metabolite Screen Not Provided


Result ID Test Result Name Result LOINC Value
Z3745 Ketamine Screen 3701-0
Z3746 Reporting Limit 19147-8
Z3747 Norketamine Screen 21421-3
Z3748 Reporting Limit 19147-8

NY State Approved


Method Name

Gas Chromatography/Mass Spectrometry (GC/MS)